石岩 助理研究员
硕士生导师
联系邮箱：shiyan@fjmu.edu.cn、shiyan202299@163.com
个人简介
石岩，男，助理研究员，硕士生导师。福建农林大学植物病理专业获博士学位。
研究领域
基于多组学探索神经遗传病的致病机制
主持/参与的项目
1.福建省自然科学基金资助项目，结构变异调控DNA甲基化在痉挛性截瘫4型中的致病机制研究，2024J01699，10万元，2024.11-2027.11，主持，在研；
2.校科技处，基于多组学研究策略探索遗传变异在平山病中的致病机制，XRCZX2022033，15万元，2023.1-2028.1，主持，在研；
3. 国家自然科学基金，基于单基因模式揭示发作性运动障碍的致病机制及干预，82330037，220万元，2024.1- 2028.12，参与，在研；
科研成果
1. Shi, Y.*, Xie, J., Jiang, J., Yan, X., Chen, X., Hong, S., Liu, J., Xu, G., Su, H., Chen, W., Wang, N., & Lin, X. (2025). A Homoplasmic MT-TV Mutation Associated with Mitochondrial Inheritance of Hereditary Spastic Paraplegia. Movement disorders : official journal of the Movement Disorder Society, 40(1), 168–173.
2. Yang, K., Liu, Y., Zhang, J., Yu, Q., Xu, F., Liu, J., Li, Y., Zhang, X., Wang, Z., Wang, N., Li, Y., Shi, Y. *, & Chen, W. J. (2025). dmTGS: Precise Targeted Enrichment Long-Read Sequencing Panel for Tandem Repeat Detection. Clinical chemistry, 71(2), 319–331.(Co-corresponding)
3. Zhi, Y., Shi, Y. *, Lu, D., & Xu, D. (2025). Neurodevelopmental Implications Underpinning Hereditary Spastic Paraplegia. CNS neuroscience & therapeutics, 31(2), e70260. (Co-first)
4. Shi, Y. *, Cao, C., Zeng, Y., Ding, Y., Chen, L., Zheng, F., Chen, X., Zhou, F., Yang, X., Li, J., Xu, L., Xu, G., Lin, M., Ishiura, H., Tsuji, S., Wang, N., Wang, Z., Chen, W. J., & Yang, K. (2024). CGG repeat expansion in LOC642361/NUTM2B-AS1 typically presents as oculopharyngodistal myopathy. Journal of genetics and genomics, 51(2), 184–196.
5. Zhang, L., Shi, Y. *, Gong, W., Zhao, G., Xiao, S., Lin, H., Li, Y., Liao, Z., Zhang, S., Hu, G., Ye, Z., Wang, H., Xia, Z., Yang, Y., Cao, H., Zhong, S., Zhang, X., & Yuan, D. (2024). The tetraploid Camellia oleifera genome provides insights into evolution, agronomic traits, and genetic architecture of oil Camellia plants. Cell reports, 43(11), 114902. (Co-first)
6. Chen Y, Shi Y*, Gao Y, Hu Y, Zhou L, Hong J, Gan S, Lin X, Chen W, Xu G, He J.(2023) Clinical and genetic heterogeneity of adult polyglucosan body disease caused by GBE1 biallelic mutations in China. Genes & diseases, 11(5), 101140. (Co-first)
7. Shi, Y. *, Qin, Y., Li, F., & Wang, H. (2022). Genome-Wide Profiling of DNA Methylome and Transcriptome Reveals Epigenetic Regulation of Potato Response to DON Stress. Frontiers in plant science, 13, 934379.
8. Shi, Y. *, Zhang, X., Chang, X., Yan, M., Zhao, H., Qin, Y., & Wang, H. (2021). Integrated analysis of DNA methylome and transcriptome reveals epigenetic regulation of CAM photosynthesis in pineapple. BMC plant biology, 21(1), 19.
9. Zhang, X., Wang, G., Zhang, S., Chen, S., Wang, Y., Wen, P., Ma, X., Shi, Y. *, Qi, R., Yang, Y., Liao, Z., Lin, J., Lin, J., Xu, X., Chen, X., Xu, X., Deng, F., Zhao, L., Lee, Y. L., Wang, R., … Ming, R. (2020). Genomes of the Banyan Tree and Pollinator Wasp Provide Insights into Fig-Wasp Coevolution. Cell, 183(4), 875–889.e17.
10. Wang, L., Shi, Y. *, Chang, X., Jing, S., Zhang, Q., You, C., Yuan, H., & Wang, H. (2019). DNA methylome analysis provides evidence that the expansion of the tea genome is linked to TE bursts. Plant biotechnology journal, 17(4), 826–835. (Co-first)
（更新于2025年9月）
